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168 Rabbit anti-human urokinase polyclonal antibody 0.5 mg
Part Number 168
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$265.00
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2 - 4 $212.00
5+ $185.50
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Description

Polyclonal rabbit antibody anti-human urokinase (abbokinase, urokinase-type Plasminogen Activator, uPA, PLAU)

Specificity

The antibody binds to human HMW-scuPA (54 kDa), HMW-tsuPA (52 kDa) and LMW-scuPA (33 kDa) with high apparent affinity (Kd= 0.1 nM) completely inhibiting the ability of urokinase to activate plasminogen. Urokinase reaction with synthetic substrate S2444 is also inhibited. The antibody is highly specific for urokinase, no crossreactions were found with other serine proteases (tissue plasminogen activator, plasmin, trypsin, chymotrypsin, elastase, thrombin). Human whole plasma or plasma proteins do not interfere with its binding to urokinase.

Preparation

Affinity purification with immobilized human urokinase. Cross-adsorption on immobilised human plasma proteins

Format

Purified and lyophilized. Contains mannitol, dextran and salts

Applications and recommended dilutions

ELISA (x5000), IHC (x50)

Reconstitution

Use 1 ml sterile pure water

Storage

Shipping at ambient temperature. Storage of lyophilized antibodies 2 years at -20C or lower

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