Mouse IgG1 monoclonal antibody against human Apolipoprotein A1 (ApoA1 — the major HDL apolipoprotein), clone 1C5, 1 mL. Reacts with human ApoA1 and intact HDL particles, with no reactivity to other human plasma proteins. The HDL counterpart to YO’s ApoB reagents (cat. 843, cat. 182, cat. 387) — together they support the ApoB / ApoA-I cardiovascular-risk ratio.
SPECIFICATIONS
Catalogue number: 851 | Host: Mouse | Target: Human
Target antigen: Apolipoprotein A1 (APOA1), including ApoA1 on intact HDL
Gene: APOA1 (11q23.3) | UniProt: P02647
Clonality: Monoclonal | Clone: 1C5 | Isotype: Mouse IgG1 | Conjugate: Unconjugated
Specificity: Reacts with human Apolipoprotein A1 and HDL; no reactivity to other human plasma proteins.
Purification: Affinity chromatography.
Format: Lyophilised from 0.01 M sodium phosphate, 0.01 M sodium borate, 0.15 M NaCl, 1% dextran, 1% mannitol | Package size: 1 mL
STORAGE / RECONSTITUTION
Reconstitute with 1 mL sterile pure water. Ships at ambient temperature. Store lyophilised antibody 2 years at -20 °C or lower; store reconstituted antibody at +4 °C up to 4 weeks, or aliquot and freeze at -20 °C. Avoid repeated freeze-thaw.
APPLICATIONS
- ELISA — capture or detection of human ApoA1 / HDL.
- Immunoassay — ApoA1 quantification in plasma or serum.
- Immuno-capture — isolation of HDL particles from plasma for downstream analysis.
APPLICATION HIGHLIGHTS — HIGH-VALUE RESEARCH NICHES
- HDL biology and reverse cholesterol transport.
- Cardiovascular risk assessment — the ApoB / ApoA-I ratio.
- HDL-particle immuno-capture for lipoproteomics.
- Lipoprotein immunoassay development.
