Rabbit polyclonal antibody against native canine (dog) collagen type I + III (heterotypic blend), affinity-purified on immobilised dog collagen I+III, 1 mL. Raised against native dog tail-tendon collagen I + III, with no cross-reactivity to other dog plasma proteins. The dual-specificity reagent for the native I/III heterotypic-fibril readout in canine tissue — veterinary fibrosis pathology, canine cardiovascular and wound-healing models, and canine collagen-biomaterial characterisation. Species companions: cat. 389 (bovine) and cat. 386 (porcine). Native-conformation specific — not suitable for denaturing conditions.
SPECIFICATIONS
Catalogue number: 775 | Host: Rabbit | Target: Dog (Canis familiaris)
Target antigen: Native canine collagen type I + type III (heterotypic blend; tail-tendon derived)
Gene: COL1A1 + COL3A1
Clonality: Polyclonal | Conjugate: Unconjugated
Specificity: Binds native dog collagen type I and III; no cross-reactivity to other dog plasma proteins. Native-conformation — not suitable for denaturing / dissociating conditions.
Purification: Affinity-purified on immobilised dog collagen type I + III.
Format: Lyophilised from 0.01 M sodium phosphate, 0.01 M sodium borate, 0.15 M NaCl, 1% dextran, 1% mannitol | Package size: 1 mL (reconstitute in 1 mL sterile water)
STORAGE / RECONSTITUTION
Reconstitute with 1 mL sterile pure water. Ships at ambient temperature. Store lyophilised antibody 2 years at -20 °C or lower; store reconstituted antibody at +4 °C up to 4 weeks, or aliquot and freeze at -20 °C. Avoid repeated freeze-thaw.
APPLICATIONS
- ELISA — total-fibrillar-collagen detection in canine tissue lysate and biomaterial extract.
- IHC (frozen sections) — canine collagen I/III histochemistry: dermal scar, cardiac and organ fibrosis.
- Cell culture / ECM staining — collagen matrix deposited by canine fibroblasts.
- Note: native-conformation antibody — not suitable for denaturing / dissociating conditions.
APPLICATION HIGHLIGHTS — HIGH-VALUE RESEARCH NICHES
- Canine veterinary fibrosis pathology — cardiac, hepatic and dermal fibrosis in dogs.
- Canine cardiovascular and myocardial-infarct models.
- Canine wound-healing and dermal-scar research.
- Canine collagen-biomaterial and xenograft characterisation.
