Purified human immunoglobulin A (IgA), 1 mg — whole-molecule IgA isolated from normal human serum. Supplied as an immunochemical reference material: ELISA standard and calibrator for total human-IgA quantification, coating antigen for secondary-antibody titration, immunogen for raising anti-human IgA antisera, and blocking / adsorption reagent. Pairs directly with the anti-human IgA antibody panel — goat anti-human IgA cat. 315, rabbit anti-human IgA cat. 395, sheep anti-human IgA cat. 541 and mouse anti-human IgA clone BFG 267 cat. 807 — and belongs to the purified immunoglobulin panel alongside human IgG cat. 697, rat IgG cat. 147, mouse IgG cat. 883, rabbit IgG cat. 700 and bovine IgG cat. 404.
SPECIFICATIONS
Catalogue number: 258 | Source: Normal human serum
Composition: Immunoglobulin A (IgA), whole molecule
Format: Purified immunoglobulin | Package size: 1 mg
STORAGE / RECONSTITUTION
Ships at ambient temperature. Store at −20 °C or lower for long-term storage. After reconstitution or thawing store at +4 °C for short-term use, or aliquot and freeze. Avoid repeated freeze-thaw.
APPLICATIONS
- ELISA standard / calibrator for total human-IgA quantification in serum, plasma, saliva, milk and mucosal secretions.
- Coating antigen and positive control for titration and QC of anti-human IgA conjugates — see cat. 315, 395, 541 and 807.
- Immunogen for raising anti-human IgA antisera and secondary conjugates.
- Blocking / adsorption reagent to remove anti-human IgA reactivity from multi-species assay systems.
- Specificity and cross-reactivity control in isotype-discriminating immunoassays, alongside human IgG cat. 697.
APPLICATION HIGHLIGHTS — HIGH-VALUE RESEARCH NICHES
- Mucosal immunology — calibration of secretory and serum IgA assays in gut, respiratory and salivary research.
- IgA nephropathy and coeliac disease research — reference material for IgA-specific serology.
- Immunodeficiency screening — standard curve material for selective IgA deficiency workflows.
- Immunoassay development — isotype specificity testing and adsorption of anti-IgA cross-reactivity.
- Vaccine and adjuvant studies — quantification of antigen-specific mucosal IgA responses.
